Hypothesis on the mechanism of resistance to fluconazole in Histoplasma capsulatum.

An AIDS patient with disseminated histoplasmosis who improved during treatment with fluconazole but remained fungemic and subsequently relapsed is described. Isolates obtained from blood during therapy showed a progressive increase in fluconazole MIC from 0.625 to 20 micrograms/ml. The pretreatment,...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Wheat, J, Marichal, P, Vanden Bossche, H, Le Monte, A, Connolly, P
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9021199/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.2.410
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