In vitro and in vivo activities of SCH 42427, the active enantiomer of the antifungal agent SCH 39304.

SCH 39304, a new triazole antifungal agent, is a 50:50 racemic mixture of two enantiomers, SCH 42427 and SCH 42426. The activities of these three compounds were compared in a series of in vitro and in vivo experiments. SCH 42427 was twofold more active in vitro against a variety of yeasts and dermat...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Loebenberg, D, Cacciapuoti, A, Parmegiani, R, Moss, E L, Menzel, F, Antonacci, B, Norris, C, Yarosh-Tomaine, T, Hare, R S, Miller, G H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1605621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.2.498
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