Hypothesis on the mechanism of resistance to fluconazole in Histoplasma capsulatum.

An AIDS patient with disseminated histoplasmosis who improved during treatment with fluconazole but remained fungemic and subsequently relapsed is described. Isolates obtained from blood during therapy showed a progressive increase in fluconazole MIC from 0.625 to 20 micrograms/ml. The pretreatment,...

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izdano v:	Antimicrob Agents Chemother
Principais autores:	Wheat, J, Marichal, P, Vanden Bossche, H, Le Monte, A, Connolly, P
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1997
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9021199/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.2.410
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