Sustained high-titer antibody responses induced by conjugating a malarial vaccine candidate to outer-membrane protein complex

The development of protein subunit vaccines to combat some of the world's deadliest pathogens such as a malaria parasite, Plasmodium falciparum, is stalled, due in part to the inability to induce and sustain high-titer antibody responses. Here, we show the induction of persistent, high-titer an...

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Bibliografski detalji
Glavni autori: Wu, Yimin, Przysiecki, Craig, Flanagan, Elizabeth, Bello-Irizarry, Sheila N., Ionescu, Roxana, Muratova, Olga, Dobrescu, Gelu, Lambert, Lynn, Keister, David, Rippeon, Yvette, Long, Carole A., Shi, Li, Caulfield, Michael, Shaw, Alan, Saul, Allan, Shiver, John, Miller, Louis H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636993/
https://ncbi.nlm.nih.gov/pubmed/17110440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608545103
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