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Immunity to Recombinant Plasmodium falciparum Merozoite Surface Protein 1 (MSP1): Protection in Aotus nancymai Monkeys Strongly Correlates with Anti-MSP1 Antibody Titer and In Vitro Parasite-Inhibitory Activity

A number of malarial blood-stage candidate vaccines are currently being tested in human clinical trials, but our understanding of the relationship between clinical immunity and data obtained from in vitro assays remains inadequate. An in vitro assay which could reliably predict protective immunity i...

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Detalhes bibliográficos
Main Authors: Singh, Sanjay, Miura, Kazutoyo, Zhou, Hong, Muratova, Olga, Keegan, Brian, Miles, Aaron, Martin, Laura B., Saul, Allan J., Miller, Louis H., Long, Carole A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539572/
https://ncbi.nlm.nih.gov/pubmed/16861644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01679-05
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