Immunity to Recombinant Plasmodium falciparum Merozoite Surface Protein 1 (MSP1): Protection in Aotus nancymai Monkeys Strongly Correlates with Anti-MSP1 Antibody Titer and In Vitro Parasite-Inhibitory Activity

A number of malarial blood-stage candidate vaccines are currently being tested in human clinical trials, but our understanding of the relationship between clinical immunity and data obtained from in vitro assays remains inadequate. An in vitro assay which could reliably predict protective immunity i...

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Bibliographische Detailangaben
Hauptverfasser: Singh, Sanjay, Miura, Kazutoyo, Zhou, Hong, Muratova, Olga, Keegan, Brian, Miles, Aaron, Martin, Laura B., Saul, Allan J., Miller, Louis H., Long, Carole A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539572/
https://ncbi.nlm.nih.gov/pubmed/16861644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01679-05
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