Phase 1 Study of Two Merozoite Surface Protein 1 (MSP1(42)) Vaccines for Plasmodium falciparum Malaria

OBJECTIVES: To assess the safety and immunogenicity of two vaccines, MSP1(42)-FVO/Alhydrogel and MSP1(42)-3D7/Alhydrogel, targeting blood-stage Plasmodium falciparum parasites. DESIGN: A Phase 1 open-label, dose-escalating study. SETTING: Quintiles Phase 1 Services, Lenexa, Kansas between July 2004...

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Detalhes bibliográficos
Main Authors: Malkin, Elissa, Long, Carole A, Stowers, Anthony W, Zou, Lanling, Singh, Sanjay, MacDonald, Nicholas J, Narum, David L, Miles, Aaron P, Orcutt, Andrew C, Muratova, Olga, Moretz, Samuel E, Zhou, Hong, Diouf, Ababacar, Fay, Michael, Tierney, Eveline, Leese, Philip, Mahanty, Siddhartha, Miller, Louis H, Saul, Allan, Martin, Laura B
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847697/
https://ncbi.nlm.nih.gov/pubmed/17415408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pctr.0020012
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