Phase 1 Study of Two Merozoite Surface Protein 1 (MSP1(42)) Vaccines for Plasmodium falciparum Malaria

OBJECTIVES: To assess the safety and immunogenicity of two vaccines, MSP1(42)-FVO/Alhydrogel and MSP1(42)-3D7/Alhydrogel, targeting blood-stage Plasmodium falciparum parasites. DESIGN: A Phase 1 open-label, dose-escalating study. SETTING: Quintiles Phase 1 Services, Lenexa, Kansas between July 2004...

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Autori principali: Malkin, Elissa, Long, Carole A, Stowers, Anthony W, Zou, Lanling, Singh, Sanjay, MacDonald, Nicholas J, Narum, David L, Miles, Aaron P, Orcutt, Andrew C, Muratova, Olga, Moretz, Samuel E, Zhou, Hong, Diouf, Ababacar, Fay, Michael, Tierney, Eveline, Leese, Philip, Mahanty, Siddhartha, Miller, Louis H, Saul, Allan, Martin, Laura B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847697/
https://ncbi.nlm.nih.gov/pubmed/17415408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pctr.0020012
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