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ShcA Mediates the Dominant Pathway to Extracellular Signal-Regulated Kinase Activation during Early Thymic Development
During thymic development, the β selection checkpoint is regulated by pre-T-cell receptor-initiated signals. Progression through this checkpoint is influenced by phosphorylation and activation of the serine/threonine kinases extracellular signal-regulated kinase 1 (ERK1) and ERK2, but the in vivo re...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
American Society for Microbiology
2006
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636838/ https://ncbi.nlm.nih.gov/pubmed/16982683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00988-06 |
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