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ShcA Mediates the Dominant Pathway to Extracellular Signal-Regulated Kinase Activation during Early Thymic Development

During thymic development, the β selection checkpoint is regulated by pre-T-cell receptor-initiated signals. Progression through this checkpoint is influenced by phosphorylation and activation of the serine/threonine kinases extracellular signal-regulated kinase 1 (ERK1) and ERK2, but the in vivo re...

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Bibliographic Details
Main Authors: Trampont, Paul, Zhang, Li, Ravichandran, Kodi S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636838/
https://ncbi.nlm.nih.gov/pubmed/16982683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00988-06
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