Tyk2 Tyrosine Kinase Expression Is Required for the Maintenance of Mitochondrial Respiration in Primary Pro-B Lymphocytes

Tyk2, a member of the Jak family of protein tyrosine kinases, is critical for the biological actions of alpha/beta interferon (IFN-α/β). Although Tyk2(−/−) mice are phenotypically normal, they exhibit abnormal responses to inflammatory challenges in a variety of cells isolated from Tyk2(−/−) mice. T...

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Detalhes bibliográficos
Main Authors: Potla, Ramesh, Koeck, Thomas, Wegrzyn, Joanna, Cherukuri, Srujana, Shimoda, Kazuya, Baker, Darren P., Wolfman, Janice, Planchon, Sarah M., Esposito, Christine, Hoit, Brian, Dulak, Jozef, Wolfman, Alan, Stuehr, Dennis, Larner, Andrew C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636766/
https://ncbi.nlm.nih.gov/pubmed/16982690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00497-06
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