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Glucose-modulated Tyrosine Nitration in Beta-Cells: Targets and Consequences

Hyperglycemia, key factor of the pre-diabetic and diabetic pathology, is associated with cellular oxidative stress that promotes oxidative protein modifications. We report that protein nitration is responsive to changes in glucose concentrations in islets of Langerhans and insulinoma beta-cells. Alt...

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Detalhes bibliográficos
Main Authors: Koeck, Thomas, Corbett, John A., Crabb, John W., Stuehr, Dennis J., Aulak, Kulwant S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759311/
https://ncbi.nlm.nih.gov/pubmed/19402213
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