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Glucose-mediated tyrosine nitration in adipocytes: Targets and consequences

Hyperglycemia, a key factor in insulin resistance and diabetic pathology, is associated with cellular oxidative stress that promotes oxidative protein modifications. We report that protein nitration is responsive to changes in glucose concentrations in 3T3-L1 adipocytes. Alterations in the extent of...

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Hlavní autoři: Koeck, Thomas, Willard, Belinda, Crabb, John W., Kinter, Mike, Stuehr, Dennis J., Aulak, Kulwant S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888280/
https://ncbi.nlm.nih.gov/pubmed/19135148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.12.010
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