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Role of Topoisomerase IIβ in the Expression of Developmentally Regulated Genes

Mice lacking topoisomerase IIβ (TopIIβ) are known to exhibit a perinatal death phenotype. In the current study, transcription profiles of the brains of wild-type and top2β knockout mouse embryos were generated. Surprisingly, only a small number (1 to 4%) of genes were affected in top2β knockout embr...

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Detalhes bibliográficos
Main Authors: Lyu, Yi Lisa, Lin, Chao-Po, Azarova, Anna M., Cai, Li, Wang, James C., Liu, Leroy F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636731/
https://ncbi.nlm.nih.gov/pubmed/16923961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00617-06
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