Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity

Overcoming preexisting immunity to vaccinia virus in the adult population is a key requirement for development of otherwise potent recombinant vaccinia vaccines. Based on our observation that s.c. immunization with vaccinia induces cellular and antibody immunity to vaccinia only in systemic lymphoid...

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Belyakov, Igor M., Moss, Bernard, Strober, Warren, Berzofsky, Jay A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1999
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10200293/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.8.4512
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