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Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity

Overcoming preexisting immunity to vaccinia virus in the adult population is a key requirement for development of otherwise potent recombinant vaccinia vaccines. Based on our observation that s.c. immunization with vaccinia induces cellular and antibody immunity to vaccinia only in systemic lymphoid...

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Bibliografiska uppgifter
Huvudupphovsmän: Belyakov, Igor M., Moss, Bernard, Strober, Warren, Berzofsky, Jay A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC16363/
https://ncbi.nlm.nih.gov/pubmed/10200293
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