Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis.

Thiolactomycin (TLM) possesses in vivo antimycobacterial activity against the saprophytic strain Mycobacterium smegmatis mc2155 and the virulent strain M. tuberculosis Erdman, resulting in complete inhibition of growth on solid media at 75 and 25 micrograms/ml, respectively. Use of an in vitro murin...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Slayden, R A, Lee, R E, Armour, J W, Cooper, A M, Orme, I M, Brennan, P J, Besra, G S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163628/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9124847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.12.2813
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