Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis.

Thiolactomycin (TLM) possesses in vivo antimycobacterial activity against the saprophytic strain Mycobacterium smegmatis mc2155 and the virulent strain M. tuberculosis Erdman, resulting in complete inhibition of growth on solid media at 75 and 25 micrograms/ml, respectively. Use of an in vitro murin...

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Bibliografiske detaljer
Main Authors: Slayden, R A, Lee, R E, Armour, J W, Cooper, A M, Orme, I M, Brennan, P J, Besra, G S
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC163628/
https://ncbi.nlm.nih.gov/pubmed/9124847
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