Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis.

Thiolactomycin (TLM) possesses in vivo antimycobacterial activity against the saprophytic strain Mycobacterium smegmatis mc2155 and the virulent strain M. tuberculosis Erdman, resulting in complete inhibition of growth on solid media at 75 and 25 micrograms/ml, respectively. Use of an in vitro murin...

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Publicat a:	Antimicrob Agents Chemother
Autors principals:	Slayden, R A, Lee, R E, Armour, J W, Cooper, A M, Orme, I M, Brennan, P J, Besra, G S
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1996
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163628/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9124847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.12.2813
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