Antimycobacterial Activities of Novel Levofloxacin Analogues

In order to investigate structure-activity relationships between antimycobacterial activities and basic substituents at the C-10 position of levofloxacin (LVFX), we synthesized a series of pyridobenzoxazine derivatives by replacement of the N-methylpiperazinyl group of LVFX with various basic substi...

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Autores principales: Kawakami, Katsuhiro, Namba, Kenji, Tanaka, Mayumi, Matsuhashi, Norikazu, Sato, Kenichi, Takemura, Makoto
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
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Mechanisms of Action: Physiological Effects
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC90023/
https://ncbi.nlm.nih.gov/pubmed/10898685
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