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Human RECQ5β helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork

The role of the human RECQ5β helicase in the maintenance of genomic stability remains elusive. Here we show that RECQ5β promotes strand exchange between arms of synthetic forked DNA structures resembling a stalled replication fork in a reaction dependent on ATP hydrolysis. BLM and WRN can also promo...

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Main Authors: Kanagaraj, Radhakrishnan, Saydam, Nurten, Garcia, Patrick L., Zheng, Lu, Janscak, Pavel
格式: Artigo
語言:Inglês
出版: Oxford University Press 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635296/
https://ncbi.nlm.nih.gov/pubmed/17003056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl677
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