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RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures

RECQ1 is the most abundant of the five human RecQ helicases, but little is known about its biological significance. Recent studies indicate that RECQ1 is associated with origins of replication, suggesting a possible role in DNA replication. However, the functional role of RECQ1 at damaged or stalled...

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Detalhes bibliográficos
Main Authors: Popuri, Venkateswarlu, Croteau, Deborah L., Brosh, Jr., Robert M., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524220/
https://ncbi.nlm.nih.gov/pubmed/23095637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22581
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