Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors.
We evaluated the antimalarial effects of vinyl sulfone cysteine proteinase inhibitors. A number of vinyl sulfones strongly inhibited falcipain, a Plasmodium falciparum cysteine proteinase that is a critical hemoglobinase. In studies of cultured parasites, nanomolar concentrations of three vinyl sulf...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8807047/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.7.1600 |
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