Inhibition of duck hepatitis B virus replication by 2',3'-dideoxy-3'-fluoroguanosine in vitro and in vivo.

The antiviral activity of 2',3'-dideoxy-3'-fluoroguanosine (FdG) or its triphosphate was evaluated in the duck hepatitis B virus (DHBV) system in vitro and in vivo. In primary DHBV-infected hepatocytes FdG results in a dose-dependent inhibition of viral replication with a nearly compl...

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Autores principales: Hafkemeyer, P, Keppler-Hafkemeyer, A, al Haya, M A, von Janta-Lipinski, M, Matthes, E, Lehmann, C, Offensperger, W B, Offensperger, S, Gerok, W, Blum, H E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC163202/
https://ncbi.nlm.nih.gov/pubmed/8851615
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