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Inhibition of duck hepatitis B virus replication by 2',3'-dideoxy-3'-fluoroguanosine in vitro and in vivo.

The antiviral activity of 2',3'-dideoxy-3'-fluoroguanosine (FdG) or its triphosphate was evaluated in the duck hepatitis B virus (DHBV) system in vitro and in vivo. In primary DHBV-infected hepatocytes FdG results in a dose-dependent inhibition of viral replication with a nearly complete inhibition...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Hafkemeyer, P, Keppler-Hafkemeyer, A, al Haya, M A, von Janta-Lipinski, M, Matthes, E, Lehmann, C, Offensperger, W B, Offensperger, S, Gerok, W, Blum, H E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163202/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8851615/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.3.792
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