Inhibition of duck hepatitis B virus replication by 2',3'-dideoxy-3'-fluoroguanosine in vitro and in vivo.

The antiviral activity of 2',3'-dideoxy-3'-fluoroguanosine (FdG) or its triphosphate was evaluated in the duck hepatitis B virus (DHBV) system in vitro and in vivo. In primary DHBV-infected hepatocytes FdG results in a dose-dependent inhibition of viral replication with a nearly complete inhibition...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Hafkemeyer, P, Keppler-Hafkemeyer, A, al Haya, M A, von Janta-Lipinski, M, Matthes, E, Lehmann, C, Offensperger, W B, Offensperger, S, Gerok, W, Blum, H E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163202/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8851615/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.3.792
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