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How effective is KRM-1648 in treatment of disseminated Mycobacterium avium complex infections in beige mice?

Although the MICs of 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin, or KRM-1648 (KRM), for Mycobacterium avium complex (MAC) were significantly lower than those of other drugs, its in vivo activity was very weak. Beginning 28 days after inoculation, beige mice that had been infected i...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Ji, B, Lounis, N, Truffot-Pernot, C, Grosset, J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163130/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834894/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.437
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