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How effective is KRM-1648 in treatment of disseminated Mycobacterium avium complex infections in beige mice?

Although the MICs of 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin, or KRM-1648 (KRM), for Mycobacterium avium complex (MAC) were significantly lower than those of other drugs, its in vivo activity was very weak. Beginning 28 days after inoculation, beige mice that had been infected i...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Ji, B, Lounis, N, Truffot-Pernot, C, Grosset, J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1996
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163130/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834894/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.437
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