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How effective is KRM-1648 in treatment of disseminated Mycobacterium avium complex infections in beige mice?

Although the MICs of 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin, or KRM-1648 (KRM), for Mycobacterium avium complex (MAC) were significantly lower than those of other drugs, its in vivo activity was very weak. Beginning 28 days after inoculation, beige mice that had been infected i...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Ji, B, Lounis, N, Truffot-Pernot, C, Grosset, J
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163130/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834894/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.437
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