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Paradoxical Lipid Dependence of Pores Formed by the Escherichia coli α-Hemolysin in Planar Phospholipid Bilayer Membranes

α-Hemolysin (HlyA) is an extracellular protein toxin (117 kDa) secreted by Escherichia coli that targets the plasma membranes of eukaryotic cells. We studied the interaction of this toxin with membranes using planar phospholipid bilayers. For all lipid mixtures tested, addition of nanomolar concentr...

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Autors principals: Bakás, Laura, Chanturiya, Alexandr, Herlax, Vanesa, Zimmerberg, Joshua
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630460/
https://ncbi.nlm.nih.gov/pubmed/16935953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.090019
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