New Cationic Lipids Form Channel-Like Pores in Phospholipid Bilayers

Two representatives of a new class of cationic lipids were found to have high pore-forming activity in planar bilayer membranes. These molecules, called BHHD-TADC and BHTD-TADC, have qualitatively similar effects on phospholipid membranes. Addition of 2.5–5 μM of either of them to the membrane bathi...

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Bibliographische Detailangaben
Hauptverfasser: Chanturiya, Alexandr, Yang, Jingping, Scaria, Puthupparampil, Stanek, Jaroslav, Frei, Joerg, Mett, Helmut, Woodle, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2003
Schlagworte:
Membranes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302743/
https://ncbi.nlm.nih.gov/pubmed/12609876
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