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Relevance of Fatty Acid Covalently Bound to Escherichia coli α-Hemolysin and Membrane Microdomains in the Oligomerization Process

α-Hemolysin (HlyA) is an exotoxin secreted by some pathogenic strains of Escherichia coli that causes lysis of several mammalian cells, including erythrocytes of different species. HlyA is synthesized as a protoxin, pro-HlyA, which is activated by acylation at two internal lysines Lys-563 and Lys-68...

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Detalhes bibliográficos
Main Authors: Herlax, Vanesa, Maté, Sabina, Rimoldi, Omar, Bakás, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757223/
https://ncbi.nlm.nih.gov/pubmed/19596862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009365
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