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Paradoxical Lipid Dependence of Pores Formed by the Escherichia coli α-Hemolysin in Planar Phospholipid Bilayer Membranes

α-Hemolysin (HlyA) is an extracellular protein toxin (117 kDa) secreted by Escherichia coli that targets the plasma membranes of eukaryotic cells. We studied the interaction of this toxin with membranes using planar phospholipid bilayers. For all lipid mixtures tested, addition of nanomolar concentr...

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Detalhes bibliográficos
Main Authors: Bakás, Laura, Chanturiya, Alexandr, Herlax, Vanesa, Zimmerberg, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630460/
https://ncbi.nlm.nih.gov/pubmed/16935953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.090019
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