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C-terminal phosphorylation controls the stability and function of p27kip1

Entry of cells into the cell division cycle requires the coordinated activation of cyclin-dependent kinases (cdks) and the deactivation of cyclin kinase inhibitors. Degradation of p27kip1 is known to be a central component of this process as it allows controlled activation of cdk2-associated kinase...

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Bibliografiske detaljer
Main Authors: Kossatz, Uta, Vervoorts, Jörg, Nickeleit, Irina, Sundberg, Holly A, Arthur, J Simon C, Manns, Michael P, Malek, Nisar P
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630410/
https://ncbi.nlm.nih.gov/pubmed/17053782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601388
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