Absolute bioavailability and metabolic disposition of valaciclovir, the L-valyl ester of acyclovir, following oral administration to humans.

Valaciclovir (Valtrex), the L-valyl ester of acyclovir, is undergoing clinical development for the treatment and suppression of herpesviral diseases. The absolute bioavailability of acyclovir from valaciclovir and the metabolic disposition of valaciclovir were investigated with healthy volunteers in...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Soul-Lawton, J, Seaber, E, On, N, Wootton, R, Rolan, P, Posner, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8593015/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.12.2759
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