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Absolute bioavailability and metabolic disposition of valaciclovir, the L-valyl ester of acyclovir, following oral administration to humans.

Valaciclovir (Valtrex), the L-valyl ester of acyclovir, is undergoing clinical development for the treatment and suppression of herpesviral diseases. The absolute bioavailability of acyclovir from valaciclovir and the metabolic disposition of valaciclovir were investigated with healthy volunteers in...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: Soul-Lawton, J, Seaber, E, On, N, Wootton, R, Rolan, P, Posner, J
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1995
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8593015/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.12.2759
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