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Absolute bioavailability and metabolic disposition of valaciclovir, the L-valyl ester of acyclovir, following oral administration to humans.

Valaciclovir (Valtrex), the L-valyl ester of acyclovir, is undergoing clinical development for the treatment and suppression of herpesviral diseases. The absolute bioavailability of acyclovir from valaciclovir and the metabolic disposition of valaciclovir were investigated with healthy volunteers in...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Soul-Lawton, J, Seaber, E, On, N, Wootton, R, Rolan, P, Posner, J
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8593015/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.12.2759
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