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Evaluation of SCH51048 in an experimental model of pulmonary aspergillosis.

The efficacy of a novel triazole, SCH51048, was assessed with a murine model of pulmonary aspergillosis and was compared with those of SCH39304 and itraconazole. A wide range of doses of SCH51048 (5 to 50 mg/kg of body weight) was evaluated. Mortality was significantly delayed in mice treated with d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Allendoerfer, R, Loebenberg, D, Rinaldi, M G, Graybill, J R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC162739/
https://ncbi.nlm.nih.gov/pubmed/7574528
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