Evaluation of SCH51048 in an experimental model of pulmonary aspergillosis.

The efficacy of a novel triazole, SCH51048, was assessed with a murine model of pulmonary aspergillosis and was compared with those of SCH39304 and itraconazole. A wide range of doses of SCH51048 (5 to 50 mg/kg of body weight) was evaluated. Mortality was significantly delayed in mice treated with d...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Allendoerfer, R, Loebenberg, D, Rinaldi, M G, Graybill, J R
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162739/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7574528/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.6.1345
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