In vivo efficacy of SM-8668 (Sch 39304), a new oral triazole antifungal agent.

SM-8668 (Sch 39304) is a new oral antifungal agent which we evaluated in comparison with fluconazole in various fungal infection models. The prophylactic effect of SM-8668 was excellent against systemic candidiasis, aspergillosis, and cryptococcosis in mice. The 50% effective dose for SM-8668 was as...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Tanio, T, Ichise, K, Nakajima, T, Okuda, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171742/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2203310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.980
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