In vivo efficacy of SM-8668 (Sch 39304), a new oral triazole antifungal agent.
SM-8668 (Sch 39304) is a new oral antifungal agent which we evaluated in comparison with fluconazole in various fungal infection models. The prophylactic effect of SM-8668 was excellent against systemic candidiasis, aspergillosis, and cryptococcosis in mice. The 50% effective dose for SM-8668 was as...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1990
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171742/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2203310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.980 |
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