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Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy

We recently described a mouse model that reproduces important pathophysiological features of mitochondrial DNA (mtDNA) mutation diseases. The gene for mouse mitochondrial transcription factor A, Tfam (also called mtTFA), a nucleus-encoded key regulator of mtDNA expression, was targeted with loxP sit...

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主要な著者: Li, Hong, Wang, Jianming, Wilhelmsson, Hans, Hansson, Anna, Thorén, Peter, Duffy, John, Rustin, Pierre, Larsson, Nils-Göran
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2000
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC16263/
https://ncbi.nlm.nih.gov/pubmed/10737799
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