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Mitochondrial DNA mutations in disease and aging

The small mammalian mitochondrial DNA (mtDNA) is very gene dense and encodes factors critical for oxidative phosphorylation. Mutations of mtDNA cause a variety of human mitochondrial diseases and are also heavily implicated in age-associated disease and aging. There has been considerable progress in...

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Podrobná bibliografie
Hlavní autoři: Park, Chan Bae, Larsson, Nils-Göran
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105550/
https://ncbi.nlm.nih.gov/pubmed/21606204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010024
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