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Mitochondrial DNA mutations in disease and aging

The small mammalian mitochondrial DNA (mtDNA) is very gene dense and encodes factors critical for oxidative phosphorylation. Mutations of mtDNA cause a variety of human mitochondrial diseases and are also heavily implicated in age-associated disease and aging. There has been considerable progress in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Park, Chan Bae, Larsson, Nils-Göran
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105550/
https://ncbi.nlm.nih.gov/pubmed/21606204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010024
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