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The role of mitochondrial DNA mutations and free radicals in disease and ageing

Considerable efforts have been made to understand the role of oxidative stress in age-related diseases and ageing. The mitochondrial free radical theory of ageing, which proposes that damage to mitochondrial DNA (mtDNA) and other macromolecules caused by the production of reactive oxygen species (RO...

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Podrobná bibliografie
Hlavní autoři: Lagouge, M, Larsson, N-G
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675642/
https://ncbi.nlm.nih.gov/pubmed/23432181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joim.12055
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