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Mitochondrial DNA copy number in human disease: the more the better?
Most of the genetic information has been lost or transferred to the nucleus during the evolution of mitochondria. Nevertheless, mitochondria have retained their own genome that is essential for oxidative phosphorylation (OXPHOS). In mammals, a gene‐dense circular mitochondrial DNA (mtDNA) of about 1...
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| Publié dans: | FEBS Lett |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8247411/ https://ncbi.nlm.nih.gov/pubmed/33314045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.14021 |
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