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Pathology during acute infections: contributions of intracellular pathogens and the CTL response

Previous work has shown how, in the case of cytotoxic T-lymphocyte (CTL) responses to persistent viral infections, pathology may arise as a consequence of cell destruction directly by the virus or indirectly due to the CTL response, leading to maximum pathology at intermediate efficacy of the immune...

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Detalhes bibliográficos
Main Authors: Ganusov, Vitaly V, Antia, Rustom
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1626233/
https://ncbi.nlm.nih.gov/pubmed/17148176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsbl.2004.0276
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