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Virus Replication Strategies and the Critical CTL Numbers Required for the Control of Infection

Vaccines that elicit protective cytotoxic T lymphocytes (CTL) may improve on or augment those designed primarily to elicit antibody responses. However, we have little basis for estimating the numbers of CTL required for sterilising immunity at an infection site. To address this we begin with a theor...

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Detalhes bibliográficos
Main Authors: Yates, Andrew J., Van Baalen, Minus, Antia, Rustom
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219614/
https://ncbi.nlm.nih.gov/pubmed/22125483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002274
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