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Dysfunction of TGF-β signaling in Alzheimer’s disease

Accumulation of β-amyloid peptide (Aβ) in the brain is believed to trigger a complex and poorly understood pathologic reaction that results in the development of Alzheimer’s disease (AD). Despite intensive study, there is no consensus as to how Aβ accumulation causes neurodegeneration in AD. In this...

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Detalhes bibliográficos
Main Authors: Das, Pritam, Golde, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1626134/
https://ncbi.nlm.nih.gov/pubmed/17080189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30284
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