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Role of TGFβ signaling in the pathogenesis of Alzheimer’s disease
Aging is the main risk factor for Alzheimer’s disease (AD); being associated with conspicuous changes on microglia activation. Aged microglia exhibit an increased expression of cytokines, exacerbated reactivity to various stimuli, oxidative stress, and reduced phagocytosis of β-amyloid (Aβ). Whereas...
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| Veröffentlicht in: | Front Cell Neurosci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623426/ https://ncbi.nlm.nih.gov/pubmed/26578886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00426 |
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