Synthesis and antitumor activity of an inhibitor of fatty acid synthase

Compared to normal human tissues, many common human cancers, including carcinoma of the colon, prostate, ovary, breast, and endometrium, express high levels of fatty acid synthase (FAS, EC 2.3.1.85), the primary enzyme responsible for the synthesis of fatty acids. This differential expression of FAS...

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Detalhes bibliográficos
Main Authors: Kuhajda, Francis P., Pizer, Ellen S., Li, Ji Nong, Mani, Neelakandha S., Frehywot, Gojeb L., Townsend, Craig A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16260/
https://ncbi.nlm.nih.gov/pubmed/10716717
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