Trophoblastic Neoplasms Express Fatty Acid Synthase, Which May Be a Therapeutic Target via Its Inhibitor C93

Fatty acid synthase (FASN) is an emerging tumor-associated marker and a promising antitumor therapeutic target. In this study, we analyzed the expression of FASN in normal and molar placentas, as well as gestational trophoblastic neoplasia, and assessed the effects of a new FASN inhibitor, C93, on c...

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Hlavní autoři: Ueda, Stefanie M., Mao, Tsui-Lien, Kuhajda, Francis P., Vasoontara, Chanont, Giuntoli, Robert L., Bristow, Robert E., Kurman, Robert J., Shih, Ie-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2009
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789637/
https://ncbi.nlm.nih.gov/pubmed/19893031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.081162
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