Cargando...
Gram-Scale Synthesis of a β-Secretase 1 (BACE 1) Inhibitor
[Image: see text] Development of a scalable synthesis of an oxazine class of β-secretase inhibitor is described. Trifluoromethylated acyloin synthesis by the reaction of a mandelic acid with trifluoroacetic anhydride in the presence of pyridine (Dakin–West reaction) was used as an efficient strategy...
Gardado en:
| Publicado en: | ACS Omega |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical Society
2017
|
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044763/ https://ncbi.nlm.nih.gov/pubmed/30023606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.6b00362 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|